"This species was previously lumped with Culex taeniopus from which it was separated by Sirivanakarn & Belkin (1980). The collection of Mitchell reported by Sirivanakarn & Jakob (1981) appears to be the first definite record for Argentina." (Mitchell & Darsie, 1985).

Disease relations: is a potential enzootic vector of Eastern Equine Encephalitis virus (EEEV) in Brazil and Trinidad (Vasconcelos et al., 1991), as well as other arboviruses (Galindo et al., 1966; Galindo & Srihongse, 1967; Srhiongse & Galindo, 1967). Subtypes of EEEV have been isolated from Culex pedroi in Argentina, Brazil, Panama, and Peru (Turell et al., 2005). The Venezuelan Equine Encephalitis virus (VEEV) was isolated in 2003 from pools of Culex pedroi in Colombia (Aguilar et al., 2011). Recently, the species was reported as a major vector of VEEV in Panamá, Venezuela, and Colombia (Torres et al. 2017).

Adults were collected on human bait, in CDC light traps supplemented with birds or small rodents, in the canopy or at ground level of forests, from Shannon traps and other unspecified traps in tropical forest, forest edges, partially forest areas, second-growth vegetation, swamp edges, and in human environment with intense agricultural activities. Adults were also found resting in holes in the forest floor. Immature stages were taken from a wide variety of habitats that were heavily or partially shaded. They were taken from the edges and interior swamps and semipermanent or temporary sites. The water was clear, reddish, or turbid, stagnant or with slow current, sometimes with scum, without aquatic vegetation or with scarce or abundant emergent (aquatic grasses), submerged, or floating vegetation, and plant debris or mud at the buttom.