Disease relations: Microfilariae of Wuchereria bancrofti were found in the proboscis of experimentally infected Coquillettidia juxtamansonia (Davis 1935).

Eggs usually adhere to aquatic plants and larvae get air from them. Coquillettidia juxtamansonia have been collected with Coquillettidia albicosta, Coquillettidia venezuelensis, Mansonia titillans and Mansonia pseudotitillans sharing the same breeding places. Adults are large, aggressive biters and mostly zoophilic, but opportunistic in their preferences.