Naupactus tucumanensis belongs to the N. leucoloma species group, revised by Lanteri & Marvaldi (1995). It differentiates from N. leucoloma because the setae of pronotum and elytra are longer and more erect; the eyes are more convex; the base of the elytra is slightly bisinuate, the humeri oblique and well-developed and the apex more acute. Corbels of the hind tibiae are open.
Populations of this species include females and males, but the former are more frequent. First instar larvae was described by Marvaldi (1998).
Causes damage on Medicago sativa L. (Fabaceae) in central Argentina (Lanteri et al. 2002a) and with Zea mays L. (Poaceae). Schinopsis quebracho-colorado (Schltdl.) F. A. Barkley & T. Mey (Anarcadiaceae) and Oenothera sp (Onagraceae) are native hosts.
It is associated with vegetation of the Chacoan and Yungas biogeographic provinces, between 400-1900m. In Buenos Aires province it occurs in the area of Tandil mountains.