Muscidae is one of the most diverse families within caliptrate flies. They are present in all bioregions from tropical environments to cold areas, passing through coastal areas and up to 5,000 m.a.s.l. The adult Muscidae can be saprophagous, predators of other insects, hematophagous, or pollinators; larvae can be predators, decomposers, phytophagous, parasitoids, etc, and can live in aquatic, semi-aquatic, and terrestrial environment.

This catalogue includes basic taxonomic information on the genera and species of the family Muscidae (Diptera: Calyptratae) present in Argentina and Uruguay. For each species we included a synonym list, geographical distribution at the provincial level, and the most relevant bibliographical references. On the map we indicate by colors the trophic guild of adult flies (hematophagous, saprophagous and predatory). We also mention if the species has relevance for forensic, medical, veterinary or agricultural sciences.